The Panne laboratory at the EMBL seeks to recruit an outstanding postdoctoral scientist in structural biology. Our research focus is directed towards the structure of macromolecular assemblies involved in the innate immune system and in epigenetic gene regulation (Panne et al., Cell 2007; Panne, Current Opinion Structural Biology, 2008; Shen et al. Structure 2009). The project focuses on the structural and biochemical characterization of regulatory complexes that are essential for the innate immune system. There are possibilities to participate in other ongoing exciting projects of high scientific impact. The laboratory is located on an international research campus in Grenoble providing one of the best structural biology environments in Europe. We employ a wide range of techniques including molecular biology, biochemistry, single-molecule fluorescence, electron microscopy, light scattering, X-ray crystallography and computing. Access to techniques such as automated expression and crystallization of proteins and protein complexes and to modern biophysical instrumentation is provided.

Candidates must hold (or soon expect to hold) a PhD in biochemistry, molecular biology, biophysics or related fields. This position requires experience in X-ray structure determination projects including phasing and knowledge in expressing and purifying proteins and/or protein complexes. The candidate should be a highly motivated individual who enjoys working as part of a collaborative and multidisciplinary team.

Contract: An initial contract of 2 years will be offered to the successful candidate. This can be renewed, depending on circumstances at the time of the review.

Closing date: 18 July 2010

To apply, please email a cover letter, CV (in English) and contact information of three professional references quoting ref. no. AC/10/PD/007 in the subject line, to application@embl.de.